Senior Principal/ Principal Scientist, Computational Safety
boehringer ingelheimRidgefield, CT
$140,000 per year
Apply nowSenior Principal/ Principal Scientist, Computational Safety
L6
boehringer ingelheimRidgefield, CTyesterday
$140,000 per year
Occupations
Computer and Information Research ScientistsMedical Scientists, Except EpidemiologistsBioinformatics ScientistsIndustries
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)Research and Development in Biotechnology (except Nanobiotechnology)Pharmaceutical Preparation ManufacturingWe are seeking a Senior Principal/ Principal Scientist, Computational Safety, to provide scientific leadership in in silico safety assessment across drug discovery and development. This role will leverage advanced multi omics data, systems toxicology and AI/ML approaches to proactively identify safety liabilities, support mechanistic understanding, improve quality target identification, and facilitate risk based decision making. As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunities for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities:
Lead and/or generate in silico target safety assessment strategy development
Develop and deliver integrated computational safety packages to support program and portfolio decisions
Advance AI/ML and multi omics–based models, including foundation models, for safety and liability prediction
Drive AI enabled Adverse Outcome Pathway (AoP) development to support mechanistic risk assessment
Proactively identify and communicate on target and off target safety risks
Collaborate closely with Toxicology, Discovery, Clinical Safety, Bioinformatics, Data Science, and IT teams
Serve as a bridge and clearly communicate complex computational insights to multidisciplinary stakeholders.
Requirements:
Ph. D. in Computational Toxicology, Computational Biology, Bioinformatics, Molecular Biology, or related field with minimum 7+ years of post-doctoral and/or industry experience in drug discovery and development and ≥3 years of experience in safety risk assessment is a must
Strong collaboration, scientific leadership, and communication skills, with the ability to translate complex computational results into actionable insights for stakeholders with diverse backgrounds
Expertise in computational toxicology, AI/ML modeling, and multi-omics (TGx) data integration
Experience with in silico safety, liability prediction, and mechanistic modeling
Familiar with toxicology related data curation, and interpretation, and knowledge of GLP toxicology and regulatory guidance will be a favorable plus Eligibility Requirements
Must be legally authorized to work in the United States without restriction.
Must be willing to take a drug test and post-offer physical (if required)
Must be 18 years of age or older Compensation Data
The base salary range for the Scientist II position is $140,000 to $222,000.The base salary range for the Scienitst III position is $170,0000 to $269,000.The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please note. Why Boehringer Ingelheim?
With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better. Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent, authentic and bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed. Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare. By being part of a team that is constantly innovating, you'll be helping to transform lives for generations.
Apply now
Level
LeadL6
Salary
$140,000 per year
Location
Ridgefield, CT
Occupation
Computer and Information Research Scientists
Industry
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Posted
yesterday
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