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Principal Engineer, VaiDA User Experience

L5

avery healthcare groupDenver, COtoday
Principal User Experience Engineer Vertex Pharmaceuticals is seeking a Principal User Experience Engineer to shape the future of VaiDA, our enterprise AI platform for employees across Vertex. This role will design and build polished, seamless interfaces for sophisticated AI and multi-agent workflows used by employees across Vertex. The ideal candidate blends strong frontend engineering expertise with exceptional UX and product instincts, translating complex backend capabilities into user experiences that are clear, intuitive, and scalable for 10,000+ employees. This is a foundational role focused on ensuring VaiDA is not only powerful, but also approachable, efficient, and trusted to use.
Key Responsibilities:
  • Design and build high-quality frontend experiences for VaiDA and related AI-driven enterprise workflows
  • Lead UX engineering strategy and frontend architecture for VaiDAOwn interaction design and prototyping for a wide spectrum of user journeys and multi-agent experiences
  • Translate sophisticated technical capabilities into clear, intuitive, and scalable interfaces
  • Create workflow visualizations that improve usability, clarity, and user confidence
  • Partner closely with product, engineering, AI, and business stakeholders to define user-centered solutions
  • Develop and refine reusable UI patterns, components, and design standards for enterprise-scale applications
  • Prototype and validate concepts quickly to inform product direction and implementation
  • Advocate for usability best practices and help raise the bar for design quality across digital products
  • Contribute to the overall product vision for VaiDA as a trusted and engaging enterprise AI experience
  • Mentor engineers and influence UX engineering best practices across teams
Required Qualifications:
  • Bachelor's degree in Computer Science, Human-Computer Interaction, Design, Engineering, or a related field; or equivalent practical experience
  • Proven experience in frontend engineering, product design engineering, or UX engineering roles
  • Strong track record of designing and building polished, user-centered interfaces for complex applications
  • Experience translating technical or data-rich workflows into clear and intuitive user experiences
  • Demonstrated ability to own interaction design and prototyping from concept through implementation
  • Strong understanding of usability, accessibility, and responsive design principles
  • Experience collaborating cross-functionally with product managers, engineers, and stakeholders
  • Ability to balance user needs, technical constraints, and business goals in a fast-paced environment
  • Excellent communication, problem-solving, and presentation skills
Technical Skills Required:
  • Modern frontend development frameworks such as React, Angular, TypeScript, JavaScript, HTML, and CSSInteraction design and frontend prototyping
  • Enterprise UI development and scalable design systemsExperience with design tools such as Figma or similar prototyping platforms
  • Workflow visualization and complex interface design
  • Usability and human-centered design practices
  • Frontend performance optimization
  • Component-based architecture and reusable UI patterns
  • Collaboration with backend and AI/agent-based systems
  • Accessibility standards and inclusive design implementation
Preferred Skills:
  • Experience designing for AI-powered products, conversational interfaces, or multi-agent systemsExperience leveraging AI-assisted tools to accelerate frontend prototyping, design exploration, or development workflows
  • Familiarity with enterprise software and internal platform experiences
  • Understanding of product strategy and user research methods
  • Experience building interfaces for data-heavy, workflow-oriented, or highly technical applications
  • Familiarity with design systems governance and frontend architecture at scale
Benefits: Vertex offers a competitive and comprehensive rewards package designed to support employees professionally and personally, which may include:
  • Competitive salary and performance-based incentives
  • Comprehensive health, dental, and vision coverage
  • Retirement and savings programs
  • Paid time off and company holidays
  • Professional development and career growth opportunities
  • Inclusive and collaborative work environment
  • Employee wellness and support programs
  • The opportunity to help shape innovative AI experiences that make a meaningful impact across VertexFlex Designation: Hybrid-Eligible Or On-Site Eligible
  • Company Information
Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
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Level

SeniorL5

Location

Denver, CO

Occupation

Web and Digital Interface Designers

Industry

Software Publishers

Posted

today

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