Senior Director, Software Product Management and Product Engineering

A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today. Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong. We are seeking a highly driven leader for one of the most critical and high-impact roles at BillionToOne: the Senior Director of Software Product Management & Product Engineering. In this role, you will lead the organization responsible for building and scaling BillionToOne's software products and platforms across both our oncology and prenatal businesses. This includes external customer-facing experiences such as provider portals and patient portals, as well as mission-critical internal software platforms such as an internal variant curation and report generation platform. This is a unique opportunity for a product-first technology leader who combines exceptional product management instincts with strong engineering leadership experience. The ideal candidate is deeply customer-centric, understands how to build scalable and elegant software systems, embraces an AI-first mindset, and has experience leveraging emerging AI capabilities to deliver differentiated customer experiences and operational advantage. This leader should also have experience managing engineering organizations while maintaining a strong product and business mindset. You will oversee both the Software Product Management and Software Product Engineering organizations, partnering closely with Clinical Product, IT/IS, Data Science, Bioinformatics, Operations, Commercial, and Executive Leadership teams to deliver category-defining software experiences and operational platforms that create a durable competitive advantage. This is a hybrid (onsite 3 days/week) position reporting directly to the Chief Product Officer.

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).The base salary range for this role is $261,102 – $304,619. This position is eligible for an annual bonus and receives a new hire equity grant of up to $260,000 at grant value, vesting over four years, plus annual equity refresh grants equal in value to the new hire grant. Together, the total four-year value of base, target bonus, and equity is up to approximately $2.0 million. We also offer competitive medical and dental coverage and a 401(k) with company match. BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. For more information about how we protect your information, we encourage you to review our Privacy Policy. BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide. Our ImpactUnity CompleteTM is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Unity ConfirmTM enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne's Fetal Cell CaptureTM Technology. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care. Our GrowthFrom $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. Our Recognition